Azathioprine
– Discussion: – prevents conversion of purine bases by suppressing synthesis of guanine and adenosine; – RA Doses: 1-2.5 mg/kg/day; – onset of action is usually 12 to 24 weeks; – discontinuation of the drug is marked by a return in disease activity; – Toxicity: – most common toxicity is gastrointestinal including nausea, anorexia, and, … Read more
