Data Trace Editor – Discussion: – growth-remaining method – straight-line graph method – arithmetic method is the simplest, but least accurate. – proximal femoral physis:: – 4 mm / yr (1/8 in/yr) – distal femoral physis: – … Read more
– Dosing: – leukemia: – 2.5 to 5 mg for children & 2.5 mg to 10 mg for adults; – continuous infusion of large amounts of methotrexate may be employed (from 250 mg to 1 g/sq m., q week), when leucovorin rescue is … Read more
– Contraindications: – Septra (Bone marrow toxicity) – Probenecid (blocks tubular secretion of methotrexate) – GI Toxicity: – GI intolerance is the most common adverse reaction; – anorexia, nausea, vomiting, diarrhea, and even unexplained wt loss – Bone Marrow Toxicity: – may occur and is … Read more
– for hypotension: – initial dose: 3-5 mg IV push; – titrate BP: given as continuous infusion; – begin at 5 ug/min; – dilute 40mg/250ml D5W; – may cause Bradycardia
– for essential hypertension; – Adult Dosing: – 250-500mg PO bid/tid (max: 2-3gm/day) or 250mg-1gm IV q4-8hr; – Precautions: – sudden withdrawl may result in significant rebound HTN; – do not use in presence of liver disease; – use smaller doses in renal failure
– may cause hemolysis in pt w/ G6PD deficiency
– Discussion: – a condition in which the there is medial displacement of the metatarsals on the cuneiform; – forefoot is adducted at the tarsal metarsal joint; – usually seen in the first year; – is bilateral in 50% of patients may be associated with hip displasia … Read more
– See: Kniest Dysplasia: – Discussion: – rare skeletal dysplasia characterized by change in body proportions w/growth; – because of the short limbs and relatively long trunk during infancy, this condition often has been confused with achrondroplasia; – unlike pts with achrondroplasia, the head and face appear normal; – severe kyphoscoliosis may develop, w/ a … Read more
– Discussion: – oral hypoglycemic agent; – note: some anesthesiologists will prefer to hold this agent on the day of surgery due to reports of uncontroled hypoglycemia during surgery; – if this medication is given the morning of surgery, then serial blood sugars need to … Read more
– similar to Methenamine Mandelate) – these are oral agents used only for suppression or prophylaxis of chronic UTI; – they are absorbed well and are excreted into the urine in high conc. – these agents have no intrinsic antibacterial activity, but at a pH of 5.5 or less, mandelic and hippuric acids are antibacterial and … Read more