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Metformin / Glucophage



- Discussion:
    - oral hypoglycemic agent;
    - note: some anesthesiologists will prefer to hold this agent on the day of surgery due to reports of uncontroled hypoglycemia during surgery;
             - if this medication is given the morning of surgery, then serial blood sugars need to be taken on a serial basis throughout the case;
    - dosage:
             - usual starting dose is 500 mg PO bid given with the morning and evening meals;
             - dosage increases should be made in increments of 500 mg each week, given in divided doses, up to a maximum of 2500 mg per day;
             - w/ higher doses, this medication should be given on a tid basis