Data Trace Editor – Discussion: – osteoclasts are found in most of bone tumors, or at least there are multinucleated cells that look like osteoclasts; – there cells are quite striking in appearance; – host bone involved by a tumor reacts to it in a very limited manner; – … Read more
– Discussion: – see management of osteochondral injuries and cartilage menu – microfracture is a knee surgery that involves the creation of multiple perforations (microfractures in the subchondral bone) in areas that are cartilage deficient. – theory behind this type of technique is that simple abrasion arthroplasty may not allow a sustained reparative response (no more than 2 weeks of healing) where … Read more
– For severe fungal infections including coccidioidomycosis, candidiasis, Cryptococcus, and others; various tinea forms; cutaneous candidiasis; vulvovaginal candidiasis; tinea versicolor; – Adult: systemic: dosage range from 200-3,600 mg/24hr IV based on diagnosis; to be administered diluted to minimum volume of 200 ml NSS; – Topical apply to affected area twice daily for 2-4 weeks; – … Read more
– See: – Penicillin Family – AntiPseudo – Adult: 2-4gm q4-6hr Injection; or 200-300 mg/kg/24hr; 1.85mEq Na/gm; – More active than Ticarcillin against Enterobacteriacae, same activity against P.aeruginosa; good activity against B.fragilis; – Diffusion from blood into CSF adequate w/ or w/o Inflammation; Ratio of CSF to Blood Level … Read more
– Discussion and Dosage: – type of reducing compound that leads to the formation of oxygen free radicals which are toxic to anaerobic bacteria; – for amebiasis, trichomoniasis, B.fragilis, C. difficile; – is effective for B.fragilis which is resistant to clindamycin, chloramphenicol, penicillin G; – amebic: 750mg … Read more
– See: Class II Agents – Discussion: – for HTN, MI, angina pectoris; beta blocking agent; – HTN dose: – 100mg PO qd in single or divided doses; may increase dosage q1-2 weeks until desired response; – usual range … Read more
– Discussion: – mild to moderate essential HTN: – edema of renal dz or cardiac failure, to potentiate effects of loop Diuretics; – inhibits NaCl resorption in corical diluting segment and in proximal tubule; HTN:2.5-5mg PO qd; – Edema: 5-20mg PO qd; – CHF: 5-10mg qd; – Potentiation of loops:2.5-10mg-titrated to effect; – Precautions: – Monitor … Read more
– Diabetic Gastroparesis: – 10mg PO 30min AC and HS for2-8 weeks prn; – GI Reflux: – 10-15mg PO 30min AC and HS; maximum duration of therapy is 12 weeks; – Prophylaxis of N/V in Cancer Chemotherapy; – IV infusion 1-2mg/kg diluted in 0.9% saline and given slowly (over 15min) 30 min before … Read more
– See Steroids – Discussion: – not used for Cerebral edema; – useful for Potassium wasting; – Dosing: – PO: 4-48mg/day depending on disease and clinical response; – IV: 30mg/kg infused over 10-20min for septic shock; – Dosage for Severe bronchospasm: – 0.5-1mg/kg initially, followed by tapering doses q4-6hr Original Articles: A Randomized, Controlled Trial … Read more
– may cause hemolysis in pt w/ G6PD deficiency