Osteopetrosis
– Discussion: – osteopetrosis is failure of osteoclastic and chondroclastic resorption; – bones become exceedingly dense; – marrow space is filled w/ unresorbed dense bone; – disease results from lack of osteoclastic resorption, leading to thickened bones & exclusion of marrow cavity; – there is absence of marrow elements & these patients are susceptible to … Read more