Data Trace Editor – Discussion: (see cartilage menu) – chondrocytes occupy lacunae distributed through the matrix; – chondrocytes are spherical in deep portion, but are flattened toward the periphery of cartilage; – peripheral lacuna may house a single chondrocyte; – deeper lacunae may contain two or more … Read more
– See: Bone Tumor Menu – Discussion: – age at presentation: – most common primary epiphyseal tumor in children is chondroblastoma; – most commonly arises between ages 10 to 30; – not infrequently, the tumor will also arise … Read more
– See: Knee Joint Menu – Discussion: – articular cartilage injury and potential for repair; – rotational forces in direct trauma is the most common cause of injury to the articular cartilage; – in adults, the tidemark zone is the weak link between the overlying cartilage and subchondral bone and therefore shearing injuries most often … Read more
– Used to reduce cholesterol; will bind bile; upto 4gm:1-6x/day; – Peds: 20-40 mg/kg/24hr PO or IV in 4 DD q6hr
– Choice of Incisions: – attempt to raise flaps so that normal skin lies at the base of the flap whereas diseased skin (nodules or cords) should lie at the flap tip; – if a flap is not to be raised, incisions should be placed directly over skin … Read more
– Indications: – long acting thiazide like diuretic used in hypertension; – edema associated w/ CHF, cirrhosis, steroid and estrogen therapy; – Adult: 50-100mg POqd; – Contraindications: allergy to sulfa drugs; – Caution with patients w/ impaired hepatic or renal function or SLE; – Peds: 2mg/kg/dose PO 3 times a week
– may be used to control severe HTN which does not respond to Nitroprusside, use Thorazine w/ caution; – begin w/ 2.5 mg IV bolus, repeating prn q 5-10 min to max dose of 15 mg; – must have liter of crystaloid ready for infussion, if profound hypotension occurs; – for psychotic, … Read more
– See: Skin Prep – Discussion: (chloroprep) – kills cells by disrupting their cell membranes and precipitating cell contents; – it has extremely low toxicity even when used on the intact skin of new borns; – in comparison to alcohols, antibacterial activity of chlorohexidine gluconate is not as rapid, but the drug remains … Read more
– for anxiety, ETOH withdrawl; Sedative; will cross react with ETOH; – Adult: Anxiety: 5-10mg PO tid/qid, or 25-50mg IM/IV tid/qid; – ETOH w/drawl: 50-100mg IM/IV; repeat 2-4hr if needed; Max dose: 300mg/24hrs; – tapper doses; Reduce dose in elderly; – relief of severe anxiety disorders: PO20-25mg tid/qid; IM/IV:50-100mg initially, then 25-50mg tid or qid … Read more
– for insomnia, used as a sedatvie especially in children; also use as preoperative sedative; sedative hypnotic, non barbiturate; – Adult: 500mg-1gm PO or PR qhs prn (max 2gm/day); – Causes gastric and mucosal irritation; – Contraindicated with marked hepatic or renal impairment, or with severe cardiac disease; – Use with caution w/concomitant oral anticoagulant use … Read more