Clindamycin/Cleocin
– Discussion: – for serious infections with Gram Neg anaerobes (B. fragilis) or staph / streptococcus infections in patients allergic to penicillin; – not good for gm neg aerobes; – clindamycin binds exclusively to the 50 S subunit of bacterial ribosomes and suppresses protein synthesis; (bacterostatic not bacterocidal); … Read more