Data Trace Editor – Second Generation Ceph – Adult: 1-2gm q4-8hr IM/IV;t1/2=.5 hr; – or try:1-2gm q6-8hr IV to max dose 12gm/day (2gm q4hr); – for surgical prophylaxis:2gm IV/IM 30min prior to surgery then 2gm q6hr for 24hr( 72hr for prosthetic arthroplasty); – Res to B. Lactamase; good for: B.fragilis, aerobic and anaerobic; N.gonorrhea, and surgery; – … Read more
– See: Third Generation Cephalosporin – Adults: 25 to 150 mg/kg/day IV; – Peds: 100-150 mg/kg/day q8hr; – good for Pseudomonas, Gm Neg Eneteric, NonEnterococci Strep; moderate to poor activity against strep; mod to good (85%) against Staph; – No activity against B.fragilis or enterococci; – Uncomplicated UTI: 250mg IV/IM q12hr; – Complicated UTI: 500mg-1gm IV/IM … Read more
– Third Generation Cephalosporin – For uncomplicate UTI: 500mg q12hr IM/IV; – for uncomplicated infection in other sites: 1 gm q8-12hr IM/IV; – For severe or refactory infections in other sites: 1gm q8hr IM/IV or 2gm q8-12hr IM/IV; – for life threatening infections: 3-4gm q8hr IV; – decrease dose with renal failure; – Good diffusion … Read more
(See: Radiographic Features of DDH) Discussion CE angle provides useful information after the age of 5 years (may be used in adults); angle formed by a line drawn from the center of the femoral head to the outer edge of the acetabular roof, and a verticle line drawn through the center of the femoral head; angle … Read more
– Second Generation Ceph – Adult: 250mg PO q8hr; may double dose w/ severe infections; – Contraindicated w/ cephalosporin allergy; – Dosing Regimens for Patients with Renal Insufficiency: (Dose for 70kg Adult {gm/dosing interval in hours}: CrCl:>80::0.5/8; CrCl:50-79::0.5/8; CrCl:30-49::0.5/8;; CrCl:10-29::0.25/8; – 50 % of dose will be excreted in urine; – Not recommended … Read more
– First Generation Ceph – Uncomplicated UTI: 1-2gm/day in single (qd) or divided doses (bid); – Moderate to Severe UTI: 2gm/day in divided doses bid; – Skin and skin suture infections: 1gm/day in single dose qd or divided dose bid; – Group A Beta hemolytic strep pharyngitis and tonsillitis: 500 mg bid for10 days; – Must … Read more
– Second Generation Ceph – Semisynthetic broad spectrum cephalosporin – Gen II. – Adult:500mg-1gm IV/IM q4-6hr to max dose of 12gm/day (2gm q4hr); – usual dose is 1gm q6hr; – Peds: 50-100 mg/kg/day q6hr; – Good diffusion from blood into CSF only with inflammation; Ratio of CSF to Blood Level (%): Normal Meninges: nil; … Read more
– See: – first generation ceph – antibiotic prophyalxis – Adult: 0.5-2gm q8hr IM/IV; t1/2=2h; Max dose: 6 gm/24hr; – surgical prophylaxis: 1gm IM/IV 30-60min before surgery and 500mg – 1gm q6-8hr afterwards for 24hr; – Peds: ( > 4 yrs): 100 mg/kg/24 hr – Caution: … Read more
– for UTI, Otitis Media, Pharyngitis, Bronchitis; – Adults: 400 mg PO qd… or … 200 mg PO bid; – Child: 8 mg/kg/day of suspension – Resistant Organism: – Psuedomonas, Gr D Strep (enterococci), Listeria, Enterobacter, Clostridia, Staph (meth res. staph); – 50 % of dose will be excreted in urine (w/ nl … Read more
– See: – Ossification of Soft Tissue and Periosteum – Metastatic Bone Tumors (prostate, thyroid, kidney, breast, lung) – Hyperparathyroidism – PTH secreting tumors (lung, kidney, ovary, colon), multiple myeloma – Vitamin D – amount of Vit D required to produce HyperCa … Read more