The Hip - book

Disaster Injuries (continued)

Tom Large, MD Ben Kam, MD C. Demonstrate knowledge of the indications for and ability to implement emergent orthopedic interventions (tourniquet, etc.)   I. Tourniquets             A. Prehospital tourniquet use shown to have significant beneficial effect on blood loss, shock, and mortality without increased risk for amputation or conversion to higher amputation levels1, 2             B. Application … Read more

Current Concepts Review: Total Ankle Arthroplasty

Foot Ankle Int. 2008 Feb;29(2):256-264   Guyer AJ, Richardson G ABSTRACT  Many orthopaedic surgeons had abandoned the use of first and second generation total ankle arthroplasties due to unacceptably high complication and failure rates as compared to arthrodesis. Recently, there has been renewed interest in ankle joint replacement as longer term outcome studies have become … Read more

Debridement

B. Define and demonstrate debridement   I. Introduction             A. Debridement derived from French verb “débrider”             B. Initially used to denote action of “cutting certain parts which—like a bridle—constrict or strangulate the organs which they cover”2,3             C. Goal of surgical debridement                         1. save lives                         2. preserve function                         3. remove contaminants … Read more

Ceftriaxone/Rocephin

– Discussion:     – third generation cephalosporin;     – adult: 1-2gm IV q12-24hr; t1/2=7.5hr; w/ long half life, allows once a day dosing, and home treatment;     – peds: 100 mg/kg/day q12 or q24hr;     – no need to change w/ renal failure;     – broad spectrum Gm neg and … Read more

Cefuroxime/Zinacef

– Discussion:     – second generation ceph     – cefuroxime is effective in therapy of cases of community-acquired pneumonia in which ampicillin-resistant H.  influenzae is a possible etiologic agent cefoxitin;     – adult dose:          – 0.75-1.5gm q6-8hr IV or 3gm q8hr IV w/ meningitis;         … Read more

Cefonicid/Monocid

– Second Generation Ceph – Semisynthetic cephalosporin: for surgical prophylaxis: – 1gm 1hr given preoperatively; – Severe infections: 2gm qd IV/IM; – Mild to Moderate infections: 1gm qd IV/IM; – Uncomplicated UTI: 500mg qd IV/IM; – Dosing Regimens for Patients with Renal Insufficiency: (Dose for 70kg Adult{gm/dosing interval in hours}):CrCl: >80::1/24;; CrCl:50-79:: 1/24;; CrCl:30-49::1/24;; CrCl:10-29::1/48;; … Read more

Cefoperazone/Cefobid

– Third Generation Cephalosporin – Do Not use alone with Pseudomonas; – Adult: 100-150mg/kg/24hr q8-12hr IV; t1/2 = 2.5hr; – Hepatic and renal excretion allows normal dosing in Renal failure; – Disulfiram reaction and hypothrombinemia; – Good diffusion from blood into CSF only with inflammation; – Dosing Regimens for Patients with Renal Insufficiency: (Dose for … Read more

Cefotaxime/Claforan

– Third Generation Cephalosporin – 100-200mg/kg/24hr; 1-2gm IV q4-6hr; – good Gm Neg coverage; Broad spectrum Gm Neg and Pos; – Treatment of gonorrhea: 1gm IV single dose; – Uncomplicated infections: 1gm IV/IM q12hr; – Moderate to severe infections:1-2gm IV/IM q8hr; – Septicemia and life threatening infections: 2gm IV q4hr; – Prevention of postoperative infections: … Read more

Cefotetan

– Gram Pos (Not enterococci, MRSA, Listeria) – Gram Neg (h. influenza, E. coli, Proteus, Klebsiella, M.catarhalis, Proteus, N.gonorrhea)     (Not Pseudomonas, Enterobacter, Serratia) – Dose: 1 gm q8hr to 2 gm q4 hr (non absorbed) IM or IV – serum binding 65-79% – Check PT time, preexisting coagulopathy is a relative contraindication