Synovial Chondromatosis

- Discussion:
    - a monarticular synovial proliferative disease which is characterized by the metaplastic conversion of cartilagenous tissue to ossified 
           loose bodies;
    - cartilagenous or osteocartilaginous metaplasia takes place w/in the synovial membrane of joints, bursae, or tendon sheaths;
    - seen most often in middle-aged men;
    - pts report pain and limitation of motion;
    - location:
           - over one-half of cases occur in the knee, followed by the elbow;
           - other common sites include the hip, shoulder, wrist and ankle;
           - when located in the foot or ankle the term "soft tissue chondroma" may be used;
    - classification:
           - early: no loose bodies but active synovial disease;
           - transitional: active synovial disease, and loose bodies;
           - late: loose bodies but no synovial disease;
    - diff dx:
           - hemangioma
           - tumoral calcinosis
           - soft tissue chondroma
           - dermatomyositis
           - hyperparathyroidism
           - hypervitaminosis D
           - idiopathic hypercalcemia

- Radiographs:
    - intraarticular loose bodies are seen in > 70%;
    - when radiographs are negative, MRI may show cartilagenous bodies;
    - MRI will show high signal on T2 weighted images;


- Treatment:
    - total open synovectomy is the treatment of choice;
    - recurrence rate is over 25%


Extra-articular synovial chondromatosis.

Synovial osteochondromatosis: a histopathological study of thirty cases.

Primary synovial chondromatosis of the ankle. A case report.

Generalized synovial chondromatosis of the knee: A comparison of removal of the loose bodies alone with arthroscopic synovectomy.

Surgery for synovial chondromatosis: 26 cases followed up for 6 years.

Synovial Chondromatosis.

Chromosome rearrangements in synovial chondromatous lesions.

Synovial osteochondromatosis of the elbow

Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Wednesday, June 20, 2012 12:44 pm