The Hip - book

DVT Treatment – low molecular weight heparins (LMWH)

Dalteparin (Fragmin) prevents formation of clots by accelerating activity of antithrombin III availability 2,500 IU or 5,000 IU/ 0.2 mL single-dose prefilled syringe 7,500 IU / 0.3 mL single-dose prefilled syringe 10,000 IU / 0.4 mL single-dose prefilled syringe 10,000 IU / 1 mL single-dose graduated syringe 12,500 IU / 0.5 mL single-dose prefilled syringe … Read more

Laboratory Findings for Infected Total Knee Replacement:

– See Laboratory Finding in Infected THR Discussion:     – WBC      – ERS     – IL-6     – C-reactive protein            – references:                     – Mark B. Coventry Award: Synovial C-reactive Protein: A Prospective Evaluation of a Molecular Marker for Periprosthetic Knee Joint Infection                      – C reactive protein and skin … Read more

Hypercoagulable States / Conditions

– See:      – Coag Pathway      – Pulmonary Embolus – Discussion:     – at greater than 40 years;     – preexisting conditions such as heart disease, obesity, carcinoma, diabetes, varicose veins, and hypertension;     – history of pre-existing embolism;     – history of prolonged immobilization;     – use of estrogens;           … Read more

DVT Risk Reduction – Hip Fracture

choice of anesthesia in elective hip surgery there is three-fold decrease in thromboembolic complications from the use of regional anesthesia and graded compression stockings reference – Prevention of thromboembolism following elective hip surgery. The value of regional anesthesia and graded compression stockings. role of heparin Low-molecular-weight heparinoid compared with warfarin for prophylaxis of deep-vein thrombosis … Read more

Glucose/Dextrose

Supplied: 1-2 amps of D50W (25-50 gm glucose); Cautions nutritional support solutions infused peripherally are usually limited to 10-12.5% Dextrose because infusion of more hypertonic solutions into peripheral veins can result in phlebitis or severe infiltration sequelae; Peds w/ Dextrose concentrations of 10-12.5% adequate calories for preterm neonates can be provided peripherally if the patient … Read more

Fondaparinux / Arixtra

– See Lovenox – Discussion:     – synthetically manufactured pentasaccharide anticoagulant;     – inhibitor of antithrombin (see coagulation cascade);     – in contrast to heparins (which inactivate factor Xa and thrombin), fondaparinux only inhibits antithrombin;     – dosage: 2.5 mg SQ q24 Effect of low molecular weight heparin (dalteparin) and fondaparinux … Read more

Erythromycin

– Discussion:     – for group A strep (pyogenes), alpha hemolytic strep and n. gonorrhea, s. pneumoniae, mycoplasma, legionnaire’s, soft tissue infection with s.aureus;     – adult: 250-500mg PO qid or 500mg-1gm IV qid;     – IV administration of erythromycin is painful and may cause thrombophlebitis;            – this … Read more