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Supplied: 1-2 amps of D50W (25-50 gm glucose);


  • nutritional support solutions infused peripherally are usually limited to 10-12.5% Dextrose because infusion of more hypertonic solutions into peripheral veins can result in phlebitis or severe infiltration sequelae;


  • w/ Dextrose concentrations of 10-12.5% adequate calories for preterm neonates can be provided peripherally if the patient can tolerate large fluid loads and maximum doses of fat emulsion;
  • Rx begins w/ 10 gm/kg/day of dextrose in older infants and children;
  • increases of 5 gm/kg/q12-24 hrs upto 30gm/kg/day may be made if there is a central venous access and normal glucose tolerance;
  • neonates may not tolerate large amounts of glucose initially & are at risk for hyperosmolar coma as result of hyperglycemia;
    • note: infants have lower renal threshold for glucose