- Blood Product Menu:
- pRBC's / Fresh Frozen Plasma / Platlets / Cryoprecipitate / Transfusion Therapy / Coag Pathway
- Methods to Decrease Transfusion:
- erythropoietin
- The effects of recombinant human erythropoietin on perioperative transfusion requirements in patients having a major orthopaedic operation.
- Use of erythropoietin to increase the volume of autologous blood donated by orthopedic patients.
- iron supplementation:
- references:
- Iron supplementation after femoral head replacement for patients with normal iron stores;
- The effect of oral iron supplementation on erythropoiesis in autologous blood donors.
- autologous blood: (see pRBC transfusion)
- in the THR study by Sculco and Gallina 1999, 82% of these patients (autologous or PAD patients) required transfusion of their own
blood (vs 50% in patients that did not donate autologous blood), but only 8% of PAD patients required allogenic transfusion;
- 34 to 45% of autologous blood was discarded;
- w/ a preop Hgb level of less than 11 g/dl about 93-96% of patients required a transfusion vs. only 52-59% of patients w/ a preop Hgb
of greater than 14 g/dl;
- w/ THR, expected transfusion requirements are 0.8 units when the Hgb level is more than 14 g/dl vs 1.6 units when Hgb level is less than 11 g/dl;
- in the prospective randomized study by DB Billote MD et al (JBJS- Am Aug 2002, p 1299), the authors noted that preop autologous donation provided
no benefit for nonanemic patients undergoing primary total hip replacement;
- preoperative autologous donation increased the likelihood of autolgous transfusion, wastage of predonated units, and costs;
- references:
- Preoperative Autologous Donation for Total Joint Arthroplasty. An Analysis of Risk Factors for Allogenic Transfusion
Hatzidakis AM, et al. J Bone Joint Surg Am. 2000;82(1):89.
- aprotinin:
- cell saver:
- references:
- Use of recombinant human erythropoietin (r-HuEPO) in a Jehovah's Witness refusing transfusion of blood products: case report.
- Reinfusion of whole blood after revision surgery for infected total hip and knee arthroplasties.
- Methylmethacrylate monomer and fat content in shed blood after total joint arthroplasty.
- Unwashed Filtered Shed Blood Collected After Knee and Hip Arthroplasties: A Source of Autologous Red Blood Cells.
- Postoperative Blood Salvage Using the Cell Saver after Total Joint Arthroplasty.
- Reinfusion of shed blood after orthopaedic procedures in children and adolescents.
- Blood salvage after total hip arthroplasty.
Outcome of massive transfusion exceeding two blood volumes in trauma and emergency surgery.
- pRBC's / Fresh Frozen Plasma / Platlets / Cryoprecipitate / Transfusion Therapy / Coag Pathway
- Indications for Blood Transfusion:
- Methods to Decrease Transfusion:
- erythropoietin
- The effects of recombinant human erythropoietin on perioperative transfusion requirements in patients having a major orthopaedic operation.
- Use of erythropoietin to increase the volume of autologous blood donated by orthopedic patients.
- iron supplementation:
- references:
- Iron supplementation after femoral head replacement for patients with normal iron stores;
- The effect of oral iron supplementation on erythropoiesis in autologous blood donors.
- autologous blood: (see pRBC transfusion)
- in the THR study by Sculco and Gallina 1999, 82% of these patients (autologous or PAD patients) required transfusion of their own
blood (vs 50% in patients that did not donate autologous blood), but only 8% of PAD patients required allogenic transfusion;
- 34 to 45% of autologous blood was discarded;
- w/ a preop Hgb level of less than 11 g/dl about 93-96% of patients required a transfusion vs. only 52-59% of patients w/ a preop Hgb
of greater than 14 g/dl;
- w/ THR, expected transfusion requirements are 0.8 units when the Hgb level is more than 14 g/dl vs 1.6 units when Hgb level is less than 11 g/dl;
- in the prospective randomized study by DB Billote MD et al (JBJS- Am Aug 2002, p 1299), the authors noted that preop autologous donation provided
no benefit for nonanemic patients undergoing primary total hip replacement;
- preoperative autologous donation increased the likelihood of autolgous transfusion, wastage of predonated units, and costs;
- references:
- Preoperative Autologous Donation for Total Joint Arthroplasty. An Analysis of Risk Factors for Allogenic Transfusion
Hatzidakis AM, et al. J Bone Joint Surg Am. 2000;82(1):89.
- aprotinin:
- cell saver:
- references:
- Use of recombinant human erythropoietin (r-HuEPO) in a Jehovah's Witness refusing transfusion of blood products: case report.
- Reinfusion of whole blood after revision surgery for infected total hip and knee arthroplasties.
- Methylmethacrylate monomer and fat content in shed blood after total joint arthroplasty.
- Unwashed Filtered Shed Blood Collected After Knee and Hip Arthroplasties: A Source of Autologous Red Blood Cells.
- Postoperative Blood Salvage Using the Cell Saver after Total Joint Arthroplasty.
- Reinfusion of shed blood after orthopaedic procedures in children and adolescents.
- Blood salvage after total hip arthroplasty.
- Transfusion Complications:
- transfusion related infectious complications:
Outcome of massive transfusion exceeding two blood volumes in trauma and emergency surgery.