- See:
- warfarin
- coags
- transfusion therapy
- Volume: Approximately 200mL;
- Dose: 2 units FFP
- Maximum admistration time: 4 hrs;
- Rate of infusion: depends on patient's clinical condition;
- Indications: Bleeding w/ labile Coagulation factor deficiencies; (Factor V or VIII)
- Note: Must allow 20-30min to thaw;
- FFP contains all clotting factors including the labile factors V and VIII as well as 250 to 400 mg of Fibrinogen;
- FFP contains anti-erythrocyte antibodies, & is given type specific product;
- after every 6 units of blood is given, two units of FFP is given, and after every ten units of blood, six units of platelets should be infused;
- effectiveness of FFP will lapse within hours, requiring administration;
- FFP has been associatted with non cardiac pulmonary edema;
- one should not administer FFP to correct clotting studies unless the patient shows excess bleeding
- Effect of fresh-frozen plasma resuscitation on cardiopulmonary function and serum protein flux.
- Fresh frozen plasma supplement to massive red blood cell transfusion.
- Fresh frozen plasma should be given earlier to patients requiring massive transfusion.