The Hip - book

Fibrosarcoma of Soft Tissue

– See: Soft Tumor Menu – Discussion:     – an invasive, malignant, spindle cell tumor which demonstrates cellular atypia, mitosis, & formation of type I collagen;     – it is less aggressive in soft tissue than in bone;     – most common soft tissue sarcoma in infants;     – lower limb … Read more

Fibrosarcoma of Bone

– Discussion:     – fibrosarcoma of bone occurs most often in adolescents or young adults;     – presents in major long bones, presenting as painful mass;     – preoperative staging studies are needed  to differentiate low grade stage I fibrosarcomas from high grade stage II lesions; – X-rays     – poorly defined, … Read more

Plantar Fibromatosis

– See: – Fibroma – Desmoplastic Fibroma – Soft Tissue Menu – Discussion: – refers to multiple fibrous benign tumors which are locally aggressive; – these are more aggresive than solitary fibroma; – these lesions often develope in the proximal limbs or the trunk; – in abdomen, the tumor is called a desmoid tumors; – … Read more

Fibrodysplasia Ossificans

– Presentation:     – shortened first toe is characteristic in fibrodysplasia ossificans progressiva;     – recognition of this consistent foot deformity can help in the early diagnosis;     – torticollis is common; – Radiographs:     – see ossification of soft tissue:     – ossification, which occurs in the fascia and … Read more

Fibrocartilage

 – Discussion: (see cartilage menu and articular cartilage)     – see tendon metaplasia to fibrocartilage;     – fibrocartilage is composed of bundles of thick clearly defined collagen fibers, along w/ intervening unicellular islands of cartilage arranged in small chains;     – it has moderate proteoglycans but low content of glycosaminoglycans (2% of dry weight).   … Read more

Fibrinogen

– Discussion:      – precursor of structural protein fibrin & is composed of duplicate sets of three chains (Aalpha, Bbeta, and gamma) linked by disulfide bonds;      – peptide-bond cleavage of fibrinopeptide A and fibrinopeptide B yields soluble fibrin;      – fibrin rapidly polymerizes into fibrin strands, ultimately forming fibrin clot that mechanically impedes blood loss

Fibrin Degradation Products (FDP)

    – See:  – Transfusion Therapy  – Fresh Frozen Plasma  – Cryoprecipitate  – Fibrin Degradation Products (FDP): – Fibrin Split Products; FSP:<10 ug/mL Increased:  – Any thromboembolic condition (DVT, MI, PE), DIC;  – Fibrinogen: 150-450 MG/dL  – Decreased: Congenital, DIC (Sepsis, Amniotic Fluid Embolism, Abruptio placenta), Surgery (Prostate, Open Heart), Neoplastic & Hematological conditions, … Read more

Fibrillations

– See: EMG Menu: – Discussions:     – fibrillations are action potentials that arise spontaneously from single muscle fibers;     – these usually occur rhythmically and are though to be due oscillations of the resting membrane potential in denervated muscles;     – are typically biphasic or triphasic waveforms that are distinguished from … Read more

FES: Criteria for Diagnosis

– Discussion:  – Dx of FES requires at least one sign from major criteria and at least four signs from the minor criteria category;   – Gurd’s Major Criteria:  – axillary or subconjuctival petechia   – occurs transiently (4-6 hours) in 50-60 % of the cases;  – hypoxemia (PaO sub 2, <60 mmHg; FiO sub 2, <= … Read more