- See: Inotropic Agents
- Discussion:
- use of this med is limited to temporary control of significant Bradycardia that is refractory to atropine;
- is the only one of the major inotropes which can decrease pulmonary vascular resistance;
- this is useful in patients w/ pulmonary HTN (esp. mitral valve patients) & patients w/ acute Right Heart Failure;
- Precautions:
- it is not indicated in the treatment of electromechanical dissociation;
- it is extremely arrhythmogenic, causing Ventricular arrhythmia's w/ even moderate dosing;
- avoid excessive HR especially with acute MI;
- vasodilation with decrease in blood pressure;
- contraindicated with Tachycardia, pulse >130 may induce ventricular arrhythmias;
- Dosage:
- infusion is prepared by adding 1-2 mg of isoproterenol to 250-500 ml of D5W and administering at 1-20 ug/min and titrate to HR;
- may begin therapy with small ?(0.2-0.5mg) IV dose;
- then begin IV infusion;
- Cardiac arrest and Cardiac Dysrhythmias:
- Dilute .2mg (1ml of 1:5000 sol) to 10ml with .9% NaCl of D5W, and inject IV 0.02-0.06mg (1-3ml);
- Shock: 1-4ug/min IV infusion, titrateto effect, or better try: