The Hip
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Cardiac

- Discussion:
- cardiovascular manifestations cause 90% of the deaths;
- major abnormality is dilatation of the ascending aorta, which usually begins in the intrapericardial portion and extends into or beyond
     aortic arch;
     - dilatation at level of valve may result in aortic regurgitation;
     - dilatation is progressive & precedes aortic dissection & rupture;
- mitral regurgitation secondary to mitral valve prolapse may also occur, and cardiac arrhythmias have been implicated as a cause of death