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- useful in patients with RA, especially those in early progressive arthritis; 
- Toxic Side Effects: 
- nephrotoxicity, proteinuria, dermatitis, stomatitis, thrombocytopenia, aplastic anemia, and erythematous maculopapular rash 

Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthritis. A controlled clinical trial.