- Discussion:
    - predisposing conditions:
            - open fracture (traumatic tibia infections)
            - sickle cell anemia
            - septic arthritis
                   - in children, distinguishing between metaphyseal osteomyelitis and septic arthritis can be problematic;
            - diabetes   (see osteomyelitis in the diabetic patient); 
    - pathophysiology:
staph aureus osteomyelitis is unique in that there is an ability to survive and hide withing osteocytes;
                    - Intracellular Staphylococcus aureus. A mechanism for the indolence of osteomyelitis.
                    - In vivo internalization of Staphylococcus aureus by embryonic chick osteoblasts. 
                    - Internalization of bacteria by osteoblasts in a patient with recurrent, long-term osteomyelitis. A case report. 
                    - Osteomyelitis and Intraosteoblastic. Staphylococcus aureus
    - classification:
            - hematogenous osteomyelitis 
            - cierny classification
            - chronic osteomyelitis 
            - tibia fracture infection
            - vertebral osteomyelitis
    - characteristics based on age:
            - osteomyelitis in infants
            - osteomyelitis in children

- Laboratory and Radiographic Workup for Osteomyelitis:
radiographic findings of hematogenous osteo
             - ref: Images in Clinical Medicine. Bone within Bone — Chronic Osteomyelitis

- Traumatic Osteomyelitis:
    - antibiotic beads vs vancomycin in calcium sulfate
    - medications for osteomyelits 
    - treatment based on location:
             - spinal osteomyelitis 
             - tibial osteomyelitis 
             - femoral osteomyelitis following IM nailing 
             - osteomyelitis of the foot
    - debridement of sequestra 
    - soft tissue coverage:
             - The Muscle Flap in the Treatment of Chronic Lower Extremity Osteomyelitis: Results in Patients Over 5 Years After Treatment
             - Local muscle flaps in the treatment of chronic osteomyelitis

- References for Osteomyelitis:
      - Osteomyelitis  
      - Surgical Treatment Osteomyelitis

 The classic: The treatment of chronic osteomyelitis with the maggot (larva of the blow fly). 1931.


Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Thursday, December 1, 2016 10:13 am