Local Anesthetic Properties for Lidocaine
- See: systemic lidocaine administration
- maximum dose: 4.5mg/kg or 300mg (28 ml of 1% solution) or 50 mL of 1% solution w/ added Epinephrine (1:200,000);
- duration of action:
- anesthetic onset in 5-30 min, lasting 2-3 hr;
- addition of sodium bicarbonate (8.4%, 10 meq/L) to 1% lidocaine may reduce the burning experienced from injection (most likely caused by acidity);
- add 1-2 ml of bicarbonate for each 10 ml of 1% lidocaine used;
- addition of epinephrine:
- epinephrine added to injectable forms for anesthesia to prolong effects & help decrease bleeding;
- must not be used on digits, penis, or ears and careful w/ HTN;
- dose: 50 mL of 1% solution w/ added epinephrine (1:200,000);
- w/ IV forms, dosage reduction is required with liver disease, CHF;
- toxicity: dizziness, confusion, slurred speech, paresthesias, convulsions associated with toxicity: > 6-8ug / ml=toxic
Serum lidocaine levels during arthroscopy using continuous irrigation with lidocaine.
Intravenous lidocaine for anesthesia in the lower extremity. A prospective study.
Anesthetic properties and toxicity of bupivacaine and lidocaine for infiltration anesthesia.
Damage to tissue defenses by a topical anesthetic agent.
A clinical comparison of lidocaine and bupivacaine.
Reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression.
Human Chondrocyte Viability After Treatment With Local Anesthetic and/or Magnesium: Results From an In Vitro Study
Original Text by Clifford R. Wheeless, III, MD.
Last updated by Data Trace Staff on Friday, December 16, 2011 3:42 pm