- See:
systemic lidocaine administration
- Discussion:
-
maximum dose: 4.5mg/kg or 300mg (28 ml of 1% solution) or 50 mL of 1% solution w/ added Epinephrine (1:200,000);
-
duration of action:
- anesthetic onset in 5-30 min, lasting 2-3 hr;
- addition of sodium bicarbonate (8.4%, 10 meq/L) to 1% lidocaine may reduce the burning experienced from injection (most likely caused by acidity);
- add 1-2 ml of bicarbonate for each 10 ml of 1% lidocaine used;
-
addition of epinephrine:
- epinephrine added to injectable forms for anesthesia to prolong effects & help decrease bleeding;
- must not be used on digits, penis, or ears and careful w/ HTN;
- dose: 50 mL of 1% solution w/ added epinephrine (1:200,000);
-
precautions:
- w/ IV forms, dosage reduction is required with liver disease, CHF;
-
toxicity: dizziness, confusion, slurred speech, paresthesias,
convulsions associated with toxicity: > 6-8ug / ml=toxic;
Serum lidocaine levels during arthroscopy using continuous irrigation with lidocaine.
Intravenous lidocaine for anesthesia in the lower extremity. A prospective study.
Anesthetic properties and toxicity of bupivacaine and lidocaine for infiltration anesthesia.
Damage to tissue defenses by a topical anesthetic agent.
A clinical comparison of lidocaine and bupivacaine.
Reducing the pain associated with local anaesthetic infiltration for open carpal tunnel decompression.
Lidocaine Exhibits Dose- and Time-Dependent Cytotoxic Effects on Bovine Articular Chondrocytes In Vitro
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