Increased: Physiologic: - Severe Exercise, 3rd Trimester, Labor, Surgery,
 
Increased: Pathologic:
   Bacterial infections (See Sepsis MI Pulmonary Infarct Crush Injury, Burn Eclampsia DKA Uremia Acute Gout Leukemia; Systemic JRA ( > 40,000)
 
Decreased: Pancytopenia Aplastic Anemia - X-ray Poisoning w/ Benzene or AntiTumor Meds Severe Overwhelming Infections - Disseminated TB, Septicemia - Acute malaria - Severe Osteomyelitis - Infectious Mono - Atypical Pneumonia - Viral Infections - Osteosclerosis, Myelofibrosis, Malignant infiltrate Meds: - B12 Folate deficiencies - Quinidine, Procainamide, Disopyramide, Lidocaine Hypoaldosteronism Hypopituitarism Dialysis, Familial decr; - Left Shift/Total PMN count; - left shift is present in the CBC when > 20% Bands are seen or when total PMN Count (Segs + Bands) is > 80%; - left shift: bacterial infection, toxemia, hemorrhage