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Esmolol (Brevibloc)

Discussion

  • for rapid control of ventricular rate (SVT) in pts w/ atrial fib or flutter in acute setting;
  • begin treatment with 500 ug/kg load over 1 min then 50 ug/kg/min for 4 min;
  • if inadequate response, repeat loading dose and follow w/ maintenance infusion of 100 ug/kg/min for 4 min;
  • titrate by repeating loading dose followed by increases in maintenance dose of 50 ug/kg/min for 4 min until desired heart rate is reached