- See: myopathic disorders:
- congenital myopathies are a group of different conditions, w/ variable genetic patterns of inheritance, that lead to muscle weakness in infancy
and early childhood;
- include central core disease, nemaline myopathy, myotubular myopathy, congenital fiber type disproportion, and centronuclear myopathy;
- children w/ congenital myopathies present as "floppy" babies in whom weakness leads to failure to achieve normal motor milestones;
- generally they improve with age, but children are never athletically adept, and they may deteriorate and die of respiratory failure
Current Concepts Review. The Diagnosis and Orthopaedic Treatment of Inherited Muscular Diseases of Childhood.