- Clinical Presentation:
- sudden onset of pain, pallor, paresthesias, variable paralysis, and absence of distal pulses;
- only 15% of all arterial emboli lodge in the upper extremity;
- sudden atraumatic onset in conjunction with atrial fib or recent MI strongly implicates an embolic event;
- origin: 70% of emboli are of cardiac origin;
- mural thrombus associated with MI
- thrombus lodged within a ventricular aneuysm
- dyskinetic atrium of atrium fibrillation;
- cardiac emboli are usually large & cause sudden acute obstruction at fairly proximal level, often bifurcation of the brachial art
- most of remainder arise from subclavian artery at the thoracic outlet due to compression from;
- fascial bands in the scalene musculature
- cervical ribs
- anomalous first ribs;
* emboli of arterial origin are smaller & travel more distally in vascular tree;
- Treatment
    - large proximal emboli
         - initiate heparin as soom as recognized
         - many large emboli are amenable to embolectomy
         - local anesthesia to expedite treatment
         - fogarty catheters, can be used as far distally as the wrist;
         - observe closely for compartment syndrome following revascularization;
         - coumadin for at least 3 months;
    - emboli distal to the wrist;
         - initially treat to reverse vasospastic component of ischemia
               - axillary block
               - digital or wrist block with marcaine
               - stellate ganglion block;
         - if no response within several hours proceed to heparin
         - if still no response and tissue loss is expected
               - discontinue heparin
               - consider thrombolysis with intra-arterial or IV urokinase
					