- Increased: 
- Volume depletion, CHF, Adrenal Insufficiency, DM, SIADH, Increased proteins (nephrosis) (upto 1.050); 
- If markedly increased (1.040-1.050), Suspect artifact or excretion of radiographic contrast media; 
- Decreased: 
- DI, Pyelonephritis, Glomerulonephritis, Waterload w/ Nl Renal Function; 
- Misc: 
- Specific gravity varies inversely with urine excretion
- In some conditions this relationship is affected: 
- Diabetes: increased volume; increased specific gravity; 
- HTN: normal volume; decreased specific gravity; 
- Early chronic renal disease: increased volume; decreased spec. gravity; 
- Interfering Factors: 
- SG highest in the AM sample 
- Elevated with Excess water loss 
- contrast media in contrasts (and dextrin): false positive