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Bone Marrow


- Discussion:
    - bone marrow signal on T1- and T2 vary with age
    - in adults,  tumor invading bone marrow will show decreased signal on T1, in contrast to normally high signal-intensity bone marrow;
           - its imporant to note that traumatic, inflammatory, and neoplastic disorders will have similar appearances;
    - some of lesions will have an increased signal intensity on T2 sequences (primary tumor, metastatic lesions, and infections) while others lesions will have low signal on T2 (leukemia, lymphoma);
    - osteonecrosis has consistent decreased signal intensity on T1 images as compared to high signal of normal marrow (see MRI of AVN of femoral head)