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Pseudohypoparathyroidism


-See:
     - Hypoparathyroidism:
     - Actions of PTH:

- Discussion:
    - lack of responsiveness to PTH due to defect in adenyl cyclase;
    - clinical picture may resemble of hypoparathyroidism;
    - due to inability of bone & kidney to respond to parathyroid hormone, hypocalcemia and hyperphosphatemia occur in spite of elevated 
           parathyroid levels;
    - pts w/ this disorder have a characteristic clinical appearance that includes short stature, round faces, & shortened 4th metacarpals;
    - subQ calcifications that may be present in pseudohypoparathyroidism not present in the idiopathic disorder