Data Trace Editor – for treatment of recurrent Ventricular Fibrillation or hemodynamically unstable ventricular Tachycardia; – Adult: Loading: 800-1600 mg/day for 1-3 weeks; – Maintenance dose: 600-800 mg/day for 1 month, then 200-400 mg/day; – Peds: 10 mg/kg/day divided q12hr PO for 7-10 days then reduce to 5 mg/kg/day divided q12hr if effective; – Average half life of … Read more
– for Asthma, bronchospasm; – Adult Loading Dose: 6mg/kg IV over 20 min; – maintenance 0.6 mg/kg/hr IV infusion; w/ CHF, Liver dz, or elderly pts maintenance dose = 0.3 mg/kg/hr IV; – will need to individualize doses; – Acute Asthmatic Attack: Load 6mg/kg IV, then 1 mg/kg/hr IV; – Watch serum values: 10-20ug/ml is … Read more
– See addition of antiobiotics to cement discussion – tobramycin: – has rapid elution of antibiotics which diminishes quickly after 2 weeks; – of interest, some bacteria will be able to survive on tobra or vanco beads alone, but generally cannot survive when both antibiotics are added to cement mixture; – the addition of 3.6 … Read more
– Specific Agents: – Neomycin – Gentamicin – Tobramycin – Amikacin – Netilmicin – Discussion: – indicated for serious Gm Neg infections caused by suseptable pseudomonas, proteus, e. coli, klebsiella, enterobacter sp., serratia, and gm neg sepsis; – tobramycin is more … Read more
– amicar may be harmful in disseminated intravascular coagulation, and this disorder should be reasonable r/o out before administration of this agent; – consider 3 – 5 gm IV load and 1 gm IV q1hr times 5 hours
for HTN possibly indicated in reperusion injury to protect against calcium paradox in crushed skeletal muscles; massive simultaneous volume replacement would be needed to prevent additional depletion of intravascular volume by these agents. K+ sparing diuretic; Adult: 5mg PO qd; increase to 10mg if needed
– See: – aminoglycosides – for short term Rx of serious infections from Gm Neg aerobes and penicillinase producing Staph; – Adult: 15 mg/kg/24hr divided over q8-12 hours; – with clearance < 50 ml/min. give dose over 12-18hr; – w/ clearance < 30 give dose over 24-36 hr; – Peds: … Read more
– see human amic studies and perisosteal grafting studies Biological resurfacing: an alternative to total joint arthroplasty. Autogenous meniscus grafts in articular cartilage defects–an experimental study. Treatment of articular defects with meniscal allografts in a rabbit knee model [Experimental study on interpositional arthroplasty using collagen membrane] Carbon fiber implants in osteochondral defects of the … Read more
– RA criteria: (if 5 out of following are present for > 6 weeks); – morning stiffness; – pain on motion, or tenderness in at least one joint; – swelling (soft tissue thickening or fluid, not bony overgrowth alone) in at least one joint; – swelling of at … Read more
(See Penicillin Family) For UTI caused by some strains of gram negative bacteria; Dose: 600 mg IV/IM q4-6hr; Not effective against P. aeruginosa, Penicillinase producing Staph aureus, H.influenza, Neisseria, or anaerobes; Note: Diffusion from Blood to CSF Good only with Inflammation