Data Trace Editor Discussion biosynthesis of collagen is initiated w/ osteoblasts; these intracellular events involve protein synthesis on endoplasmic reticulum to form 3 polypeptide chains, which make up protocollagen; protocollagen is hydroxylated to form procollagen, which is glyco-sylated at the endoplasmic reticulum; degree of hydroxylation of the lysine residue is important in that it will determine the number … Read more
– See: cavovarus deformity – Discussion: – coleman block test evaluates hindfoot flexibility and pronation of forefoot; – initial deformity is in the forefoot followed by subsequent changes in the hindfoot; – test is performed by placing the patient’s foot on wood block, 2.5 to 4 cm thick, with … Read more
– for reduction of serum cholesterol levels with primary hypercholesterolemia; – binds bile salts; – Adults:15-30gm/day divided into 2-4 doses; (need to mixed with beverages)
– Discussion: – the biosynthesis of collagen involves many complex processes that are subject to biologic control; – these processes can be disrupted at any point by metabolic disorders such as: – scurvy; – lathyrism; – genetic collagen diseases: … Read more
– See: Infections of the Hand – Discussion: – type of web space infection, which involves both palmar and dorsal sides; – frequently arises from a distal palmar callus, but spreads to the dorsal side; – spread of infection is limited by palmarly by the adherence of the palmar … Read more
Analgesic Anti-Anxiety Anti-Convulsant Anti-Depressant Tricyclics Antiemetics Anti-Histamines Anti-Parkinson Sedatives/Hypnotics Antitussives Anti-Pyschotics Opiods – Discussion: – tricyclic antidepressants may inhibit the metabolism of neuroleptic agents, just as neuroleptics may inhibit metabolism … Read more
Coagulation Labs – Labs: PT/PTT/BT Thrombin Time FDP/Fibrinogen – See: – Bld Prod Menu – Fresh Frozen Plasma – Platlets – Coag Pathway – Hypercoagulable states – Vit K – DDAVP
– See: – deep venous thrombosis – hypercoagulable states XII + Surface: intrinsic path: heparin/ PT | XIIa … Read more
– Discussion: (see GoutPal.com) – colchicine is used to treat acute gout; – mechanism of action involves inhibition of MSU-induced chemotactic factor release by PMNs; – in addition to treatment of acute gout, prophylactic administration of low doses of colchicine is effective in reducing the frequency of multiple attacks; – disadvantages: its onset of action … Read more
– See: Characteristics of Metals and Implants: – Discussion: – cobalt based alloys are highly resistant to corrosion and esp to attack by chloride within crevices; – cobalt based alloys may fail because of Fatigue frx (but less often than stainless steel stems)