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Wheeless' Textbook of Orthopaedics
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Succinylcholine


- Precautions: - because succinylcholine causes an increase in intra gastric pressure that may lead to gastric aspiration, crycothyroid pressure should be applied; - also causes increase in intraocular pressure and in relatively contra- indicated with injuries in an open globe; - increases intracranial pressure; - Precautions w/ Spinal Cord Injury: - w/ possible cervical spine injury, the Sellick maneuver should not be applied, and therefore, perhaps succinylcholine should not be used; - because denervated muscles have supersensivity to acetylcholine, manifests as sustained contractions and a massive release of potassium, succinyl- choline can precipitate hyperkalemic crises and should be avoided in first 6 months; - sustained depolarization caused by succinylcholine causes ion channels ion channels to remain open producingn an elevation in serum K of of approx 0.5 mEq/l; - therefore, succinylcholine should be avoided w/ ARF, burns, or spinal cord injuries;



Original Text by Clifford R. Wheeless, III, MD.