- Bone Tumor Menu
- Discussion:
- unusual benign osseous tumor;
- it resembles osteoid osteoma in some respects buts is larger ( >2 cm);
- unlike osteoid osteoma:
- occurs in older adolescents and young adults;
- osteoblastoma usually does not cause localized night pain, and when pain occurs, pain is usually not relieved by ASA;
- intense bony reaction that is seen w/ osteoid osteoma, does not occur with osteoblastoma;
- osteoblastoma more often located in the posterior elements of vertebra;
- osteoblastoma will not resolve spontaneously;
- sites of involvement: spine, femur, bone of the foot;
- an associated soft tissue mass may be seen in about 25% of patients;
- in rare cases, malignant transformation is possible;
- Radiographic Studies:
- X-rays:
- show radiolucent lesion which is surrounded by a thin margin of reactive bone that may have expanded - aneurysmal appearance;
- radiographic diff dx: osteoid osteoma, ABC, EOG, GCT, & Osteosarcoma.
- bone scan: shows intense radioisotope uptake that helps localize the lesion;
- CT Scan: confirms preoperative diagnosis and helps determine surgical approach;
- angiography: is used for staging aggressive tumors of spine;
- Histology:
- reveals scattered mitotic figures;
- proliferation of immature plump osteoblasts;
- prominent vascular & stromal tissue component & giant cells and broad osteoid seams
- Treatment:
- en bloc marginal excision is treatment of choice;
- active tumors are more likely to recur if intracapsular resection is performed;
- risk of recurrance after marginal excision of aggresive stage 3 is 30-50%;
- radiation therapy or chemotherapy is not effective
Osteoid-osteoma and osteoblastoma of the spine.
Scoliosis caused by benign osteoblastoma of the thoracic or lumbar spine.
Benign osteoblastoma: range of manifestations.
Osteoblastoma of the spine.
Osteoid osteoma and osteoblastoma. Current concepts and recent advances.