-
Bone Tumor Menu
- Discussion:
- unusual benign osseous tumor;
- it resembles
osteoid osteoma in some respects buts is larger ( >2 cm);
- unlike osteoid osteoma:
- occurs in older adolescents and young adults;
- osteoblastoma usually does not cause localized night pain, and when pain occurs, pain is usually not relieved by ASA;
- intense bony reaction
that is seen w/
osteoid osteoma, does not occur with osteoblastoma;
- osteoblastoma more often located in the posterior elements of vertebra;
- osteoblastoma will not resolve spontaneously;
- sites of involvement: spine, femur, bone of the foot;
- an associated soft tissue mass may be seen in about 25% of patients;
- in rare cases, malignant transformation is possible;
- Radiographic Studies:
-
X-rays:
- show
radiolucent lesion which is surrounded by a thin margin of reactive bone that may have expanded - aneurysmal appearance;
- radiographic diff dx:
osteoid osteoma,
ABC,
EOG,
GCT, &
Osteosarcoma.
-
bone scan: shows intense radioisotope uptake that helps localize the lesion;
-
CT Scan: confirms preoperative diagnosis and helps determine surgical approach;
-
angiography: is used for staging aggressive tumors of
spine;
- Histology:
- reveals scattered mitotic figures;
- proliferation of immature plump osteoblasts;
- prominent vascular & stromal tissue component & giant cells and broad osteoid seams
- Treatment:
- en bloc marginal excision is treatment of choice;
- active tumors are more likely to recur if intracapsular resection is performed;
- risk of recurrance after marginal excision of aggresive stage 3 is 30-50%;
- radiation therapy or chemotherapy is not effective;
Osteoid-osteoma and osteoblastoma of the spine.
Scoliosis caused by benign osteoblastoma of the thoracic or lumbar spine.
Benign osteoblastoma: range of manifestations.
Osteoblastoma of the spine.
Osteoid osteoma and osteoblastoma.
JH Healey. COOR. Vol 204. 1986. p 76-85.
Osteoblastoma of the foot and Ankle.
HT Temple MD et al.
Foot and Ankle International. Vol 19. No 10. Oct 1998. p 698.
