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Wheeless' Textbook of Orthopaedics
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Metoprolol/Lopressor



- See: Class II Agents

- Discussion:
    - for HTN, MI, angina pectoris; beta blocking agent;
    - HTN dose:
              - 100mg PO qd in single or divided doses; may increase dosage q1-2 weeks until desired response;
              - usual range is 100-450mg/day;
    - angina:
              - 100mg PO qd in 2 divided doses initially, increased prn at weekly intervals;
              - max dose: 400 mg/day;
              - acute MI: 5mg IV bolus at 2min intervals 3times (total 15mg IV), then 25-50mg PO q6hr x 48hr, then 100mg PO bid;
    - contraindications:
              - heart block greater than first degree;
              - sinus bradycardia,
              - cardiogenic shock, CHF;




Original Text by Clifford R. Wheeless, III, MD.