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Hypothyroidism



- Hypothyroidism in Infants and Children:
    - in the newborn period, hypothyroidism manifests itself as cretinism;
    - infant is described as sluggish, has a short stature, coarse hair, protruding tongue and protuberant abdomen;
    - retardation of growth late appearance of secondary ossification centers which may fragment and increased increased SCFE;
    - in some cases, there will be absence of the distal femoral and proximal tibial epiphysis
    - in the skull, wormian bones and prolonged separation of sutures may be encountered;
    - similar changes may be seen in mucopolysaccharidoses:
    - in children there may be fragmented, irregular epiphysis (epiphyseal dysgenesis), which may resemble Legg-Calve-Perthes disease;
    - in older children, hypothyroidism may resemble the changes seen in Perthes Disease and may actually lead to to SCFE;

- Thyroid Panel

- Medications:
    - synthroid