- historically has been the most common cause of infection in children between 3 months and 3 years of age;
- currently infections due to this organism have decreased due to widespread use of a vaccine;
- in the study by Peltola H, et al. (1998), the incidence of haemophilus influenza septic arhtritis was 0% after 10 years of routine vaccination;
- Reduced incidence of septic arthritis in children by Haemophilus influenzae type-b vaccination. Implications for treatment.
- PRP-D vaccine given at 3, 4, and 6 months;
- Treatment Options:
- septic arthritis secondary to influenzae usually responds very rapidly to treatment;
- high levels of antibiotics are obtained after intravenous administration;
- some patients w/ h. influenzae septic arthritis may have concomitant meningitis;
- CSF examination is important and the antibody chosen should be able to cross the blood-brain barrier;
- specific agents:
- cefotaxime TMP/SMX IMP
- ceftriaxone cipro cefuroxime
Original Text by Clifford R. Wheeless, III, MD.
Last updated by Data Trace Staff on Thursday, November 29, 2012 1:56 pm