The Hip: Preservation, Replacement and Revision

H. influenza



- Discussion:
    - historically has been the most common cause of infection in children between 3 months and 3 years of age;
    - currently infections due to this organism have decreased due to widespread use of a vaccine;
           - in the study by Peltola H, et al. (1998), the incidence of haemophilus influenza septic arhtritis was 0% after 10 years of routine vaccination;
                 - Reduced incidence of septic arthritis in children by Haemophilus influenzae type-b vaccination. Implications for treatment.

- Vaccine:
    - PRP-D vaccine given at 3, 4, and 6 months;

- Treatment Options:
    - septic arthritis secondary to influenzae usually responds very rapidly to treatment;
    - high levels of antibiotics are obtained after intravenous administration;
    - some patients w/ h. influenzae septic arthritis may have concomitant meningitis;
    - CSF examination is important and the antibody chosen should be able to cross the blood-brain barrier;
    - specific agents:
          - cefotaxime  TMP/SMX IMP
          - ceftriaxone cipro  cefuroxime
          - augmentin
          - cefaclor
          - TMP/SMX



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Thursday, November 29, 2012 1:56 pm