- Discussion:
- historically has been the most common cause of infection in children between
3 months and 3 years of age;
- currently infections due to this organism have decreased due to widespread use of a vaccine;
- in the study by H. Peltola et al. 1998, the incidence of haemophilus influenza septic arhtritis was 0% after
10 years of routine vaccination;
- Reduced incidence of septic arthritis in children by H. influenza type B vaccination.
H. Peltola et al.
JBJS. Vol 80-B. No 3. May 1988. p 471.
- Vaccine:
- PRP-D vaccine given at 3, 4, and 6 months;
- Treatment Options:
- septic arthritis secondary to influenzae usually responds very rapidly to treatment;
- high levels of antibiotics are obtained after intravenous administration;
- some patients w/ h. influenzae septic arthritis may have concomitant meningitis;
- CSF examination is important and the antibody chosen should be able to cross the blood-brain barrier;
-
specific agents:
-
cefotaxime
TMP/SMX IMP
-
ceftriaxone cipro
cefuroxime
-
augmentin
-
cefaclor
-
TMP/SMX
