- Bone Tumor Menu
- also known as desmoid tumor;
- is a rare tumor that that can involve bone or soft tissue;
- is locally aggressive but does not metastasize;
- soft tissue involvement:
- tends to arise from the abdomen, shoulder, and axilla;
- rarely occurs distally;
- noted to be associated w/ pregnancy;
- osseous involvement:
- it occurs primarily in young adults;
- typically develops as aggressive stage 3 lesion;
- it behaves similar to its soft tissue counter part, (Fibromatosis);
- location: tibia & fibula are most common sites;
- centrally located metaphyseal or diaphyseal lesion;
- lesion is surrounded by a thin margin of minimally reactive bone, and may have a trabeculated appearance;
- tumor may go on to penetrate the thin cortical shell, but eventually it extends through the cortex into soft tissues;
- differential diagnosis:
- giant cell tumor of bone
- fibrosarcoma of bone;
- dense & irregularly arranged collagen bundles w/ infrequent fibrocytes;
- may resemble fibromatosis;
- mitoses, vascularity, and necrosis are unusual microscopic findings;
- differential diagnosis: fibrosarcoma of bone;
- treatment of choice is excision with a wide margin;
- recurrence after curettage is frequent, with invasion of soft tissue;
- in the study by Pritchard et al 1996, there were recurrences in 2/13 patients that had wide resection vs 9/19 patients that had a marginal resection;
- radiation therapy:
- serves as a useful adjunct to surgical resection;
- radiation may be indicated by itself for inoperative tumors, or residual disease after operative debulking
Desmoplastic fibroma of bone. A report of eight cases and review of the literature.
Musculoaponeurotic fibromatosis. A report of 28 cases and review of the literature.
Extra-abdominal desmoid tumors: a report of 234 cases.
Desmoid tumors in childhood.
Local Control of Extra-Abdominal Desmoid Tumors
Original Text by Clifford R. Wheeless, III, MD.
Last updated by Data Trace Staff on Friday, June 1, 2012 2:58 pm