- See:
-
Bone Tumor Menu
-
Fibroma:
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Fibromatosis:
- Discussion:
- also known as desmoid tumor;
- is a rare tumor that that can involve bone or soft tissue;
- is locally aggressive but does not metastasize;
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soft tissue involvement:
- tends to arise from the abdomen, shoulder, and axilla;
- rarely occurs distally;
- noted to be associated w/ pregnancy;
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osseous involvement:
- it occurs primarily in young adults;
- typically develops as aggressive
stage 3 lesion;
- it behaves similar to its soft tissue counter part, (
Fibromatosis);
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location: tibia &
fibula are most common sites;
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radiographs:
- centrally located metaphyseal or diaphyseal lesion;
- lesion is surrounded by a thin margin of minimally reactive bone, and may have a trabeculated appearance;
- tumor may go on to penetrate the thin cortical shell, but eventually it extends through the cortex into soft tissues;
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differential diagnosis:
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giant cell tumor of bone
-
fibrosarcoma of bone;
- Histology:
- dense & irregularly arranged collagen bundles w/ infrequent fibrocytes;
- may resemble
fibromatosis;
- mitoses, vascularity, and necrosis are unusual microscopic findings;
- differential diagnosis:
fibrosarcoma of bone;
- Treatment:
- treatment of choice is excision with a wide margin;
- recurrence after curettage is frequent, with invasion of soft tissue;
- in the study by Pritchard et al 1996, there were recurrences in 2/13 patients that had wide resection vs 9/19 patients that had a marginal resection;
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radiation therapy:
- serves as a useful adjunct to surgical resection;
- radiation may be indicated by itself for inoperative tumors, or residual disease after operative debulking;
Desmoplastic fibroma of bone. A report of eight cases and review of the literature.
Musculoaponeurotic fibromatosis. A report of 28 cases and review of the literature.
Extra-abdominal desmoid tumors.
Desmoid tumors in childhood. [Review]
Local Control of Extra-Abdominal Desmoid Tumors D.J. Pritchard MD, A.G. Nascimento MD, and I.A. Peterson MD JBJS Vol. 78-A No. 6. June 1996.
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