- See: Essentials in Osteodynamics"
- bone remodeling functions reshaping or replacement of of bone during growth and following injury;
- in the first year of life, almost 100% of the skeleton is replaced;
- in adults, remodeling procedes at about 10% per year;
- bone responds to functional demands and muscle attachments;
- w/ remodeling, bone will be added where needed and removed where it is not required;
- bone remodeling begins w/ bone resorption
, followed by subsequent by bone formation;
- remodeling process occurs w/ a specific sequence of events termed the Bone multicellular unit
- sequence of events;
- remodeling may begin w/ parathyroid hormone
resorb bone removing both organic and inorganic
components are removed;
- subsequently, new bone by osteoblasts
, replacing bone that was resorbed;
- Wolfe's Law:
- described by Julius Wolff in 1868.
- law holds that every change in the form or function of a bone is followed by adaptive changes in its internal architecture and its external shape
Original Text by Clifford R. Wheeless, III, MD.