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Urokinase

- See: Thrombolytic Therapy: Pharmocological Agents for Vascular Surgery
- Dose: 
- load w/ 4,400 units/kg IV bolus overe 10 min;
- load w/ 50,000 units IV bolus into the occluded vessel, then infuse at 50,000 units/hr; 
- maintenance dose: 4,4000 units/kg for 12-24 hrs 


Two urokinase dose regimens in native arterial and graft occlusions: initial results of a prospective, randomized clinical trial

Increased limb salvage with intraoperative and postoperative ankle level urokinase infusion in acute lower extremity ischemia.