Home » Orthopaedics » CIS- Platin CIS- Platin - See: Chemotherapy Agents: Impact of two cycles of preoperative chemotherapy with intraarterial cisplatin and intravenous doxorubicin on the choice of surgical procedure for high-grade bone sarcomas of the extremities. IIB osteosarcoma. Current management, local control, and survival statistics--Sao Paulo, Brazil. Intraarterial cisplatin in the management of stage IIB osteosarcoma in the pediatric and adolescent age group.