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OXAZEPAM/SERAX



for anxiety with depression or ETOH withdrawl; 
Adult:10-15mg PO tid/qid; with severe anxiety or ETOH withdrawl try up to 30mg tid/qid; this is a metabolite of diazepam, must reduce w/ elderly;
Contraindicated with pyschoses; 
Avoid concomitant use of ETOH, or other CNS depressant drugs; 
Note slow onset of action, t/2= 5-21hr;
No active metabolites; 
Also note hepaticmetabolism: no oxidation needed, only conjugation w/ glucuronides