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Cyclo-oxigenase



- Discussion:
    - aspirin & other nonsteroidal antiinflammatory drugs block biosynthesis of prostaglandins and thromboxane A(sub 2) by inhibiting 
           cyclooxygenase enzyme;
    - ASA covalently acetylates cyclooxygenase, inhibiting it irreversibly, whereas other NSAIDs act reversibly on the cyclooxygenase