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Deep Venous Thrombosis (DVT) – Overview

Discussion

Prevalence

Is prophylaxis necessary following major procedures?

References

Risks based on specific procedures

Prognosis of cancer with venous thromboembolism

  • in the study by Sorensen HT, et al, the authors studied the prognosis of survival of patients who received a diagnosis of cancer at the same time as or after an episode of venous thromboembolism
    • their survival was compared w/ that of patients with cancer who did not have DVT (control patients), who were matched in terms of type of cancer, age, sex, and year of diagnosis
    • of 668 patients who had cancer at the time of an episode of DVT, 44.0 % of those with data on the spread of disease (563 patients) had distant metastasis, as compared with 35.1 % of 5371 control patients
    • in the group with cancer at the time of DVT, the one-year survival rate was 12 %, as compared with 36 % in the control group (P<0.001), and the mortality ratio for the entire follow-up period was 2.20 (95 % CI, 2.05 to 2.40)
    • patients in whom cancer was diagnosed within one year after an episode of venous thromboembolism had a slightly increased risk of distant metastasis at the time of the diagnosis (prevalence ratio, 1.23 and a relatively low rate of survival at one year (38% vs. 47% in the control group; p < 0.001)
    • cancer diagnosed at the same time as or within one year after an episode of venous thromboembolism is associated with an advanced stage of cancer and a poor prognosis
    • reference Prognosis of Cancers Associated with Venous Thromboembolism

(see also: Coagulation Cascade; Pulmonary Embolus)

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