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Aspirin for DVT

Aspirin for DVT:

   - Basic Science:
        - Why does aspirin decrease the risk of venous thromboembolism? On old and novel antithrombotic effects of acetyl salicylic acid.
        - Aspirin for prevention and treatment of venous thromboembolism
        - Antiplatelet therapy in prevention of cardio- and venous thromboembolic events.
        - Thromboembolic prophylaxis in total joint arthroplasty

   - Preoperative ASA
        - Safety of peri-operative low-dose aspirin as a part of multimodal venous thromboembolic prophylaxis for total knee and hip arthroplasty.

   - Reduction of Infection with ASA
        -
Administration of Aspirin as a Prophylaxis Agent Against Venous Thromboembolism Results in Lower Incidence of Periprosthetic Joint Infection.

   - Papers which show that ASA is effective for DVT prophylaxis:

        - Fatal pulmonary embolism following elective total hip arthroplasty: a 12-year study.
        - Thromboembolism Prophylaxis in Hip Arthroplasty: Routine and High Risk Patients.
        - Aspirin in the primary prophylaxis of venous thromboembolism in surgical patients
        - What's New in Venous Thromboembolic Prophylaxis Following Total Knee and Total Hip Arthroplasty? An Update.
        - DVT prophylaxis after TKA: routine anticoagulation vs risk screening approach - a randomized study.
        - Risk of venous thromboembolism after shoulder arthroplasty in the Medicare population
        - Deep-vein thrombosis prophylaxis in foot and ankle surgery: what is the current state of practice?
        - Aspirin versus anticoagulation for prevention of venous thromboembolism major lower extremity orthopedic surgery: a systematic review and meta-analysis.
        - Aspirin combined with mechanical measures to prevent venous thromboembolism after total knee arthroplasty: a randomized controlled trial.
        - Administering aspirin, rivaroxaban and low-molecular-weight heparin to prevent deep venous thrombosis after total knee arthroplasty.
        - Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial.
        - Incidence of symptomatic thromboembolic disease after patellofemoral arthroplasty
        - Asian venous thromboembolism guidelines: prevention of venous thromboembolism.
        - Risk early warning and multimodal prevention of postoperative venous thromboembolism for hip fractures
        - Aspirin for the prophylaxis of venous thromboembolic events in orthopedic surgery patients: a comparison of the AAOS and ACCP guidelines with review of the evidence.
        - Thromboembolic events are uncommon after open treatment of proximal humerus fractures using aspirin and compression devices.
        - Venous thromboembolic disease after total hip and knee arthroplasty: current perspectives in a regulated environment.
        - Venous thromboembolic prophylaxis for hip fractures.
        - Aspirin for the prevention of recurrent venous thromboembolism: the INSPIRE collaboration.
        - Aspirin and compression devices versus low-molecular-weight heparin and PCD for VTE prophylaxis in orthopedic oncology patients.
        - Efficacy and safety of aspirin in prevention of venous thromboembolism after total joint arthroplasty
        - Aspirin prophylaxis for thromboembolic disease after total joint arthroplasty
        - Symptomatic thromboembolism after one-stage bilateral THA with a multimodal prophylaxis protocol.
        - Mechanical calf compression and aspirin prophylaxis for total knee arthroplasty
        - The incidence and prevention of symptomatic thromboembolic disease following unicompartmental knee arthroplasty.
        - The benefit of aspirin chemoprophylaxis for thromboembolism after total knee arthroplasty
        - Aspirin for preventing the recurrence of venous thromboembolism.
        - Aspirin and the prevention of venous thromboembolism.
        - Aspirin: An Alternative for Pulmonary Embolism Prophylaxis After Arthroplasty?
        - Fatal Pulmonary Embolism following Achilles Tendon Repair: A Case Report and a Review of the Literature.
        - Aspirin: an alternative for pulmonary embolism prophylaxis after arthroplasty?
        - Aspirin for elective hip and knee arthroplasty: a multimodal thromboprophylaxis protocol
        - Incidence of venous thromboembolism in elective foot and ankle surgery with and without aspirin prophylaxis.
        - Safety and efficacy of multimodal thromboprophylaxis following total knee arthroplasty: a comparative study of preferential aspirin vs. routine coumadin chemoprophylaxis.
        - Survey of prophylaxis against venous thromboembolism in adults undergoing hip surgery.
        - Aspirin prophylaxis and surveillance of pulmonary embolism and deep vein thrombosis in total hip arthroplasty.
        - Prophylaxis of deep-vein thrombosis after total hip replacement. Dextran and external pneumatic compression compared with 1.2 or 0.3 gram of aspirin daily.
        - High and low-dose aspirin prophylaxis against venous thromboembolic disease in total hip replacement.
        - Collaborative overview of randomised trials of antiplatelet therapy--III: Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients. Antiplatelet Trialists' Collaboration.
        - Aspirin prophylaxis for thromboembolic disease after total joint arthroplasty.
        -
Aspirin for thromboprophylaxis after primary lower limb arthroplasty: early thromboembolic events and 90 day mortality in 11,459 patients.
       
- Aspirin as Thromboprophylaxis in Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis
        -
Aspirin Can Be Used as Prophylaxis for Prevention of Venous Thromboembolism After Revision Hip and Knee Arthroplasty
        -
Aspirin Is as Effective as and Safer Than Warfarin for Patients at Higher Risk of Venous Thromboembolism Undergoing Total Joint Arthroplasty.
        -
Low-Dose Aspirin Is Effective Chemoprophylaxis Against Clinically Important Venous Thromboembolism Following TJA

  - Papers that show the ASA is not effective:
        - Little impact of antiplatelet agents on venous thromboembolism after hip fracture surgery
        - A prospective comparison of warfarin to aspirin for thromboprophylaxis in total hip and total knee arthroplasty