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Cartilage Growth

Discussion

  • growth involves either or both of two processes;

Appositional Growth

  • new cartilage is formed at cartilage surface by cells derived from┬áchondroblasts of perichondrium;
  • w/ maturation, majority of cartilage growth is primarily appositional;

Interstitial Growth

  • increase in internal mass of cartilage by activity of chondrocytes that multiply within their lacunae;
  • in mature cartilage, cellular turnover rate is exceedingly low;
  • protein polysaccharide undergoes constant synthesis and degraded