- Discussion:
- numerous multinucleated giant cells, proliferative stroma, areas of necrosis, reactive peripheral bone, & occassional mitotic figures in the
stroma (but no mitotic figures in the giant cells);
- stromal cells appear elongate with oval nuclei;
- giant cells may resemble osteoclasts;
- Histologic Differential Dx:
- ABC, PVS, & TB will have multinucleated giant cells;
- tuberculous giant cells (Langhans) has peripherally located nuclei