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Phenylbutazone/Butazolidin, Azolid

- Symptomatic treatment of acute gouty arthritis; rheumatoid spondylitis;
- musculoskeletal disorders (peritendinitis, bursitis); acute perivascular inflamation;
- NSAIA; dosage: 300-600 mg/day in 3-4 divided doses;
- should reduce maintenance dose to minimum effective dose (maximum 400mg/day)
- Note: erythematous maculopapular rash;
- Note: use w/ caution in pts over 40 yrs; ocular and otic reactions may occur;
- Hematologic toxicity may be severe (aplastic anemia); long term therapy is not recommended;
- Contraindications include: pts w/ incipient cardicac failure, blood dyscrasias, pancreatitis, drug include: parotitis stomatitis, polymyalgia rheumatica, temporal arteritis, senility, drug allergy, severe, renal, cardiac, hepatic disease, h/o PUD