Tumoral Calcinosis



- See: Ossification of Soft Tissue and Periosteum:

- Discussion:
    - heritable dz characterized by periarticular metastatic calcification;
    - typically the shoulders and hips are affected most often;
    - vascular and visceral calcification does not occur;
    - hyperphosphatemia may play a role in this disorder;

- Clincal Presentation:
    - affects blacks w/ positive family history, most often;
    - disease manifests before age 20 years;
    - tend to have multiple lesions;
    - soft tissue tumors of ectopic calcification are usually painless and grow at variable rates;
    - masses may be hard and may attached to the deep fascia;
    - since the deposits are extracapsular, joint ROM is not impaired;

- Lab:
    - hyperPhosphatemia and increased serum calcitriol levels are present in some patients;

- X-ray:
    - densely calcified lobules that are confined to soft tissues;
    - radiographically these masses are similar to those seen in renal failure



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, September 13, 2011 12:17 pm