- See:
Bone Tumor Menu
- Discussion:
- bone tumor derived from reticuloendothelial elements of marrow;
- it presents in middle age;
- causes localized bone pain w/ tenderness & effussion in adjacent joints;
- Radiographs:
- poorly defined, permeative, osteolytic tumor w/ minimal periosteal reaction;
- Diff Dx:
-
osteomyelitis
- metastatic carcinoma
-
Ewing's sarcoma
-
MFH
-
Fibrosarcoma of bone
- Histology:
- large, foam filled histiocytes with numerous mitoses and scant stroma;
- reticulum stains are positive;
- Periodic Acid Schiff
(PAS) stains are negative;
- Treatment:
-
stage I tumors are treated with radiation therapy alone;
- chemotherapy is added for more advanced tumors;
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Histiocytic lymphoma (reticulum-cell sarcoma) of bone. Current
strategy for orthopaedic surgeons.
