Propanolol/Inderal



- See: Class II Agents

- Discussion:
     - nonselecive beta blocker;
     - for PSVT & for VF / VT w/o pulse after standard Rx fails:

- Dose:
      - 1.0 mg IV q5min to total dose of 0.1 mg/kg;
      - HTN: 40mg PO bid initially, then 120-140mg/day;
      - angina: 10-20mg PO qid; increase dosage at 3-7 day intervals prn;
      - average dose is 160mg/day;
      - post MI prophylaxis: 180-240mg/dayin 2-3 divided doses;
      - dysrhythmias: 10-30mgPO qid;
      - hypertrophic subaortic stenosis: 20-40mg qid;
      - migraine: 40mg PO bid;
      - tremor: 10mg po bid;
      - may be used with nitroglycerin
      - aortic dissection:
            - 0.5mg IV followed by 1mg IV q5min until pulse pressure is reduced to 60mm Hg or to a total dose of 0.15mg/kg,
                   in any 4hr period, with maintenencedose q4-6hr;

- Contraindications:
      - contraindicated w/ use of verapamil (causes asystole);
      - cardiogenic shock, sinus bradycardia, greater than 1st degree AV block, bronchial Asthma, CHF



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Monday, December 19, 2011 12:47 pm