presents
Wheeless' Textbook of Orthopaedics
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PRAZEPAM/CENTRAX




    for anxiety disorders; Benzodiazepine related to chlordiazepoxide;
Adult: 5-10mg PO 3 or 4 times qd; 20-50mg PO as single bed time dose
to minimize daytime drowsiness; CNS depressant activity may make some
activities requiring concentration dangerous for patients (driving);
Note that this drug designed for slow conversion to active product,
peak: 4-12hr after dose; Note very slow onset of action, t/2=
36--200hr; Note 1 active metabolite;



Original Text by Clifford R. Wheeless, III, MD.