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Wheeless' Textbook of Orthopaedics

Phytonadione/Vit K



- Discussion:
      - for correction of PT from: warfarin & hyperalimentation;
      - w/ parental treatment, prothrombin deficiency is controled in 4-8hr, normalized in 24 hrs;
      - watch for IV anaphyllaxis, give slowly;
      - patients who require brief reversal of anticoagulation from warfarin therapy are more easily treated by infusion of FFP;

- Adult: Anticoag Prothrombim Deficiency:
      - 2.5-10 mg PO or 10-50 mg IV, slowly; (some authors advocate 0.5 mg IV Vit K)
      - hyperalimenation: 10mg IM or IV q week;

















Original Text by Clifford R. Wheeless, III, MD.